中 文 姓 名：林彥佑
英 文 姓 名：Yen-You, Lin
研 究 專 長：膀胱癌、關節炎、動物實驗模式、自體免疫性疾病
電 子 信 箱：chas6119@mail.ntou.edu.tw
學經歷：
中國醫藥學大學 運動醫學系 2019~2021
中國醫藥學大學 學院醫學系藥理學科 2021~2024
主要授課課程：
研究項目簡介：
目前研究計畫聚焦脂肪因子Apelin (APLN)在膀胱癌(Bladder cancer, BLCA)腫瘤進展中的分子機制與治療策略。在過去的研究背景上肥胖（BMI每增加5 kg/m²）使BLCA相對風險升1.03，每10.4 kg/m²增10%風險。在台灣NHIRD資料顯示BMI≥30患者pT3風險增1.5倍，40-60歲族群5-10% BLCA病例相關。本研究聚焦肥胖相關脂肪因子APLN在BLCA腫瘤進展中的分子機制與治療策略。該脂肪因子APLN過去被證實高表達與BLCA不良預後相關。同時在整合Gene Expression Omnibus (GEO, GSE13507)、The Cancer Genome Atlas資料，證實APLN可促進BLCA的自噬(autophagy)和侵襲(invastion)能力。APLN/APJ路徑可能為促進BLCA的自噬(autophagy)和侵襲(invastion)能力。相關研究顯示APLN高表達與BLCA不良預後相關。因此初步結果顯示T24/5637細胞以APLN處理，進行wound healing、Transwell、qPCR/WB等證實APLN可以促進BLCA的autophagy和invastion而否經由APLN/APLN Receptor (APJ)路徑影響怎需要藥理學上的驗證。另外我們探討長鏈非編碼Long non-coding (Lnc) RNA -競爭性內源性Competing endogenous (ce) RNA在BLCA的角色。過去研究說明LncRNA-miRNA-mRNA-ceRNA在BLCA普遍存在並在病程中扮演關鍵機制。因此我們也初步篩選出CCAT1在APLN誘發後明顯上升。再調閱GSE190079中也發現膀胱腫瘤組織中的CCAT1 (Lnc RNA)表現顯著高於鄰近正常組織。利用線上資料庫分析發現CCAT1能與has-miR 181a-5p、has-miR 181b-5p、has-miR 345-5p及has-miR 595形成潛在ceRNA互作網絡，因此可以做為CCAT1-ceRNA互作網絡的機制探討。為驗證上述假設，我們將建立小鼠MB49腫瘤模式和結合病理和分子生物學技術深入探討APLN-CCAT1-ceRNA的作用機制評估是否可為 BCLA 潛在的治療策略。
期刊論文：
完整著作: https://scholar.google.com/citations?user=iUbmrlUAAAAJ&hl=zh-TW
1. Wei-Cheng Chen, Li-Chai Chen, You-Shan Tsai, Yen-Po Chen, Yen-Lien Chen,Chin-Chu Chen, Yen-You Lin, Tzu-Ching Chang, Chen-Ming Su, Chih-HsinTang (2026, Feb). Fermented Clostridium butyricum GKB7 InhibitsOsteoarthritis Induced by Anterior Cruciate Ligament Transection in aPreclinical Model. International Journal of Medical Sciences, 23(4):1190-1197..(SCI, 59/332, MEDICINE, GENERAL & INTERNAL). NSTC 113-2320-B-039-049-MY3.
2. Kun-Tsan Lee, Chien-Min Chen, Chih-Hsin Tang, Yen-You Lin, Tzu-ChingChang, Min-Huan Wu, Sunny Li-Yun Chang (2026, Jan). Oral administration of soybean okara extract reduces osteoarthritis pain and progression in rats. International Journal of Medical Sciences, 23(1); 243-252. (SCI, 59/332, MEDICINE, GENERAL & INTERNAL). NSTC 113-2320-B-039-049-MY3.
3. Kun-Tsan Lee, Chin-Jung Hsu, Li-Chai Chen, Li-Ya Lee, Wan-Ping Chen, Yu-Wen Chen, Chin-Chu Chen, Yen-You Lin, Tzu-Ching Chang, Chen-Ming Su, Chih-Hsin Tang (2026, Jan). Efficacy of Combined Hericium erinaceus Mycelium and Undenatured Type II Collagen in Reducing Osteoarthritis Progression in a Preclinical Animal Model. International Journal of Medical Sciences, 23(3):815-823.. (SCI, 59/332, MEDICINE, GENERAL & INTERNAL). NSTC 113-2320-B-039-049-MY3.
4. Ya-Hsin Wu, Yueh-Hsiung Kuo, Yen-You Lin, Tzong-Ming Shieh, Tzu-Ching Chang, An-Chen Chang, Ju-Fang Liu, Chih-Hsin Tang (2025, Nov). Antcin K suppresses proinflammatory cytokines expression via the PI3K, Akt and NF-κB pathways in human gingival fibroblasts: implications for periodontitis treatment. Cell Death Discovery. (SCI, 42/204, CELL BIOLOGY). NSTC 113-2314-B-039-013.
5. Chia-Chia Chao, Pei-Wen Peng, Yen-You Lin, An-Chen Chang (2025, Sep). Effects of sesamin on the chemosensitivity, invasiveness and immune evasion mechanism of human lung adenocarcinoma.. International Journal of Molecular Medicine, 56(5), 194. (SCI, 39/195, MEDICINE, RESEARCH & EXPERIMENTAL). NSTC 110-2314-B-341-001-MY2.
6. Kuang-Yu Chou, An-Chen Chang, I Thomas, Sheng Hwang, Te-Fu Tsai, Chao-Yen Ho, Hsiu-Wen Liu, David Achudhan, Chih-Hsin Tang, Yen-You Lin (2025, Aug). ABCC6 Transporter Contributed to Cisplatin Resistance on Bladder Cancer. International Journal of Medical Sciences, 22(15); 3895. (SCI, 59/332, MEDICINE, GENERAL & INTERNAL). Shin Kong Wu Ho-Su Memorial Hospital: 2022SKHBDR002. 本人為通訊作者.
7. Tien-Huang Lin, Shan-Chi Liu, Yuan-Li Huang, Chao-Yang Lai, Xiu-Yuan He, Chun-Hao Tsai, Yi-Chin Fong6, Hsi-Chin Wu, An-Chen Chang, Yen-You Lin, Chih-Hsueh Lin, Chih-Hsin Tang (2025, Jun). Apelin facilitates integrin αvβ3 production and enhances metastasis in prostate cancer by activating STAT3 and inhibiting miR-8070. International Journal of Biological Sciences, 21(9): 4117-4128.. (SCI, 26/319 BIOCHEMISTRY & MOLECULAR BIOLOGY).
8. Yen-You Lin, Chien-Chung Huang, Chih-Yuan Ko, Chun-Hao Tsai , Jun-Way Chang, David Achudhan, Chih-Hsin Tang (2025, Mar). Omentin-1 modulates interleukin expression and macrophage polarization: Implications for rheumatoid arthritis therapy. International Immunopharmacology, 149 (2025) 114205. (SCI, 54/352, pharmacology & pharmacy). MOST 110-2320-B-039-022-MY3. 本人為第一作者.
9. Ya-Hsin Wu, Fátima Daniela Marroquín Ramírez, Yen-You Lin, Tzong-Ming Shieh, Tzu-Ching Chang, Chih-Hsin Tang (2025, Feb). Betulin inhibits the production of inflammatory cytokines in human gingival fibroblasts and ligatureinduced periodontitis. International Immunopharmacology, 147(2025), 114018. (SCI, 54/352 PHARMACOLOGY & PHARMACY). NSTC 113-2314-B-039-013.
10. Ting-Kuo Chang, Trung-Loc Ho, Yen-You Lin, Le Huynh Hoa Thuong, Kuan-Ying Lai, Chun-Hao Tsai, Chih-Chuang Liaw,8*, Chih-Hsin Tang (2025, Jan). Ugonin P facilitates chondrogenic properties in chondrocytes by inhibiting miR-3074-5p production: implications for the treatment of arthritic disorders. International Journal of Biological Sciences, 2025; 21(4): 1378-1390.. (SCI, 26/319 Biochemistry & Molecular Biology ). NSTC 113-2314-B-195-014.
11. Shan-Chi Liu, Tung-Ying Wu, Trung-Loc Ho, Chun-Hao Tsai, Wen-Hui Chung, Yen-You Lin, Yang-Chang Wu, Chih-Hsin Tang (2024, Nov). Isolated from Antrodia cinnamomea, 25S-antcin K suppresses the production of inflammatory cytokines and cartilage degradation in rheumatoid arthritis. Journal of Functional Foods, 122,(2024), 106473. (SCI, 31/112, NUTRITION & DIETETICS). NSTC 112-2320-B-039-035-MY3.
12. Yen-You Lin, Wu Chih-Ying, You-Shan Tsai, Chin-Chu Chen, Tzu-Ching Chang, Li-Chai Chen, Hsien-Te Chen, Chin-Jung Hsu, Chih-Hsin Tang (2024, Sep). The joint protective function of live-and dead-Lactobacillus plantarum GKD7 on anterior cruciate ligament transection induces osteoarthritis. Aging (Albany NY), 16(18):12559–12573. (SCI, 24/74, GERIATRICS & GERONTOLOGY). MOST 110-2320-B-039-022-MY3. 本人為第一作者.
13. Zhi-Hong Wen, Chi-Chieh Tang, Yen-You Lin, Zhi-Kang Yao, Shih-Peng Hsieh, Gar-Hwa-Lai, Wu-Fu Chen, Yen-Hsuan Jean (2024, Jul). Effects of Etanercept on Experimental Osteoarthritis in Rats: Role of Histone Deacetylases. CARTILAGE, 2024 Jul 26:19476035241264012.. (SCI, 36/139, ORTHOPEDICS). NSTC 105-2314-B-475-001.
14. Li‐Chai Chen, Yen‐You Lin, You‐Shan Tsai, Chin‐Chu Chen, Tzu‐Ching Chang, Hsien‐Te Chen, Chin‐Jung Hsu, Chih‐Hsin Tang (2024, Jun). Live and Dead Clostridium butyricum GKB7 Diminish Osteoarthritis Pain and Progression in Preclinical Animal Model. Environmental Toxicology, 39(11) 4927-4935. (SCI, 39/106, TOXICOLOGY). NSTC 110-2320-B-039-022-MY3. 本人為第一作者.
15. Sung‐Lin Hu, Louis Anoop Thadevoos, Trung‐Loc Ho, Yen‐You Lin, Hsien‐Te Chen, Chien‐Chung Huang, Chen‐Ming Su, Chih‐Hsin Tang (2024, Jun). FGF23 facilitates IL‐1β synthesis in rheumatoid arthritis through activating PI3K, Akt, and NF‐κB pathways. Environmental Toxicology, 39(1), 3283-3291. (SCI, 39/106, TOXICOLOGY).
16. Chih-Yang Lin, Kun-Tsan Lee, Yen-You Lin, Chun-Hao Tsai, Chih-Yuan Ko, Yi-Chin Fong, Sheng-Mou Hou, Wei-Li Chen, Chien-Chung Huang, Chih-Hsin Tang (2024, Mar). NGF facilitates ICAM-1-dependent monocyte adhesion and M1 macrophage polarization in rheumatoid arthritis. International Immunopharmacology, 130, 111733. (SCI, 54/352, PHARMACOLOGY & PHARMACY).
17. David Achudhan, Yu-Liang Lai, Yen-You Lin, Yuan-Li Huang, Chun-Hao Tsai, Trung-Loc Ho, Chih-Yuan Ko, Yi-Chin Fong, Chien-Chung Huang, Chih-Hsin Tang (2024, Mar). CXCL13 promotes TNF-α synthesis in rheumatoid arthritis through activating ERK/p38 pathway and inhibiting miR-330-3p generation. Biochemical Pharmacology, 221, 116037.
18. Chih-Yuan Ko, Yen-You Lin, David Achudhan, Jun-Way Chang, Shan-Chi Liu, Chao-Yang Lai, Yuan-Li Huang, Chun-Hao Tsai, Yi-Chin Fong, Hsien-Te Chen, Kun-Tsan Lee, Chien-Chung Huang, Ting-Kuo Chang, Chih-Hsin Tang (2023, Oct). Omentin-1 ameliorates the progress of osteoarthritis by promoting IL-4-dependent anti-inflammatory responses and M2 macrophage polarization. International Journal of Biological Science, 19(16), 5275-5289. 本人為第一作者.
19. Nan-Fu Chen, Yen-You Lin, Zhi-Kang Yao, Chung-Chih Tseng, Yu-Wei Liu, Ya-Ping Hung, Yen-Hsuan Jean, and Zhi-Hong Wen (2023, Aug). Oral Administration of Protease-Soluble Chicken Type II Collagen Ameliorates Anterior Cruciate Ligament Transection–Induced Osteoarthritis in Rats. Nutrients, 15(16), 3589. Taiyen Biotech Co., Ltd., Taiwan: N107; N112013. 本人為第一作者.
20. Jun-Way Chang, Yen-You Lin, Chun-Hao Tsai, Shan-Chi Liu, Xiu-Yuan He, Yi-Syuan Wu, Chien-Chung Huang, Chih-Hsin Tang (2023, Jul). Nesfatin-1 stimulates BMP5 expression and osteoclastogenesis in rheumatoid arthritis. Biochemical Pharmacology , 2023 Jul 20;115687.. (SCI, 40/277, PHARMACOLOGY & PHARMACY). MOST 111-2314-B-039-038.
21. Chang-Lun Huang, David Achudhan, Po-I Liu, Yen-You Lin, Shan-Chi Liu, Jeng-Hung Guo, Chun-Lin Liu, Chih-Ying Wu, Shih-Wei Wang, Chih-Hsin Tang (2023, Jun). Visfatin upregulates VEGF-C expression and lymphangiogenesis in esophageal cancer by activating MEK1/2-ERK and NF-κB signaling. Aging-US, Jun 7;15.. (SCI, 15/54, GERIATRICS & GERONTOLOGY). China Medical University Hospital: DMR-112-081.
22. Jun-Way Chang, Shan-Chi Liu, Yen-You Lin, Xiu-Yuan He, Yi-Syuan Wu, Chen-Ming Su, Chun-Hao Tsai, Hsien-Te Chen, Yi-Chin Fong, Sung-Lin Hu, Chien-Chung Huang, Chih-Hsin Tang (2023, Jan). Nesfatin-1 Stimulates CCL2-dependent Monocyte Migration And M1 Macrophage Polarization: Implications For Rheumatoid Arthritis Therapy. International Journal of Biological Sciences, Int J Biol Sci 2023; 19(1):281-293.. (SCI, 28/297, BIOCHEMISTRY & MOLECULAR BIOLOGY). MOST 110-2320-B-039-022-MY3.
23. Sunny Li-Yun Chang, Po-Jen Yang, Yen-You Lin, Ya-Jing Jiang, Po-I Liu, Chang-Lun Huang, Shun-Fa Yang, Chih-Hsin Tang (2022, Oct). Genetic Associations of Visfatin Polymorphisms with EGFR Status and Clinicopathologic Characteristics in Lung Adenocarcinoma. International Journal of Environmental Research and Public Health, 19(22), 15172. (SCI, 100/279, ENVIRONMENTAL SCIENCES). MOST 109-2320-B-341-002.
24. Yen-You Lin, Sunny Li-Yun Chang, Shan-Chi Liu, David Achudhan, You-Shan Tsai, Shih-Wei Lin, Yen-Lien Chen, Chin-Chu Chen, Jun-Way Chang, Yi-Chin Fong, Sung-Lin Hu, Chih-Hsin Tang (2022, Aug). Therapeutic Effects of Live Lactobacillus plantarum GKD7 in a Rat Model of Knee Osteoarthritis. , 14(15), 3170. (SCI, 15/90, NUTRITION & DIETETICS). China Medical University Hospital: DMR-111-108. 本人為第一作者.
25. Sunny Li-Yun Chang, Yen-You Lin, Shan-Chi Liu, You-Shan Tsai, Shih-Wei Lin, Yen-Lien Chen, Chin-Chu Chen, Chih-Yuan Ko, Hsien-Te Chen, Wei-Cheng Chen, Chih-Hsin Tang (2022, Jul). Oral Administration of Clostridium butyricum GKB7 Ameliorates Signs of Osteoarthritis in Rats. Cells, 11(14), 2169.. (SCI, 51/195, CELL BIOLOGY). China Medical University Hospital: DMR-110-176. 本人為第一作者.
26. David Achudhan, Sunny Li-Yun Chang, Shan-Chi Liu, Yen-You Lin, Wei-Chien Huang, Yang-Chang Wu, Chih-Hsin Tang, Chien-Chung Huang, Chun-Hao Tsai, Chih-Yuan Ko, Yueh-Hsiung Kuo. (2022, Jun). Antcin K inhibits VCAM-1-dependent monocyte adhesion in human rheumatoid arthritis synovial fibroblasts. Food & Nutrition Research. (SCI, 72/143, FOOD SCIENCE & TECHNOLOGY; 58/90, NUTRITION & DIETETICS). MOST 110-2320-B-039-022-MY3.
27. Shang-Yu Yang, Chi-Jung Fang, Yu-Wen Chen, Wan-Ping Chen, Li-Ya Lee, Chin-Chu Chen, Yen-You Lin, Shan-Chi Liu, Chun-Hao Tsai, Wei-Chien Huang, Yang-Chang Wu, and Chih-Hsin Tang (2022, Jun). Hericium erinaceus Mycelium Ameliorates In Vivo Progression of Osteoarthritis. Nutrients, 2022, 14, 2605.. (SCI, 15/90, NUTRITION & DIETETICS ). China Medical University: CMU110-ASIA-02.
28. Kwei-Jing Chen, Ming-Hong Hsieh, Yen-You Lin, Michael Yuan-Chien Chen, Ming-Yu Lien, Shun-Fa Yang * and Chih-Hsin Tang * (2022, Apr). Visfatin Polymorphisms, Lifestyle Risk Factors and Risk of Oral Squamous Cell Carcinoma in a Cohort of Taiwanese Males. International Journal of Medical Sciences, 19(4):762-768.. (SCI, 75/329, MEDICINE, GENERAL & INTERNAL). MOST 110-2320-B-039-022-MY3.
29. David Achudhan, Shan‐Chi Liu, Yen‐You Lin, Hsiang‐Ping Lee, Shih‐Wei Wang, Wei‐Chien Huang, Yang‐Chang Wu, Yueh‐Hsiung Kuo, Chih‐Hsin Tang (2022, Jan). Antcin K inhibits VEGF‐dependent angiogenesis in human rheumatoid arthritis synovial fibroblasts. Journal of Food Biochemistry, 46(1):e14022.. (SCI, 179/296, BIOCHEMISTRY & MOLECULAR BIOLOGY; 58/143, FOOD SCIENCE & TECHNOLOGY). China Medical University: CMRC-CHM-2-2.
30. David Achudhan, Shan-Chi Liu, Yen-You Lin, Chien‐Chung Huang, Chun‐Hao Tsai, Chih-Yuan Ko, Yueh-Hsiung Kuo, Chih-Hsin Tang (2021, Nov). Antcin K inhibits TNF-α, IL-1β and IL-8 expression in synovial fibroblasts and ameliorates cartilage degradation: Implications for the treatment of rheumatoid arthritis. Frontiers in Immunology, 15;12:790925.. (SCI, 33/161, IMMUNOLOGY). MOST 110-2320-B-039-022-MY3.
31. Kun-Tsan Lee, Bo-Cheng Chen, Shan-Chi Liu, Yen-You Lin, Chun-Hao Tsai, Chih-Yuan Ko, Chih-Hsin Tang, Kwong-Chung Tung (2021, Sep). Nesfatin-1 facilitates IL-1β production in osteoarthritis synovial fibroblasts by suppressing miR-204-5p synthesis through the AP-1 and NF-κB pathways. Aging (Albany NY), 13(18):22490-22501.. (SCI, 72/194, CELL BIOLOGY). MOST 108-2320-B-039-065.
32. Chien-Chung Huang, Tzu-Ting Tseng, Shan-Chi Liu, Yen-You Lin, Yat-Yin Law, Sung-Lin Hu, Shih-Wei Wang, Chun-Hao Tsai, Chih-Hsin Tang (2021, Aug). S1P Increases VEGF Production in Osteoblasts and Facilitates Endothelial Progenitor Cell Angiogenesis by Inhibiting miR-16-5p Expression via the c-Src/FAK Signaling Pathway in Rheumatoid Arthritis.. cells, 10(8):2168.. (SCI, 51/194, CELL BIOLOGY). MOST 108-2314-B-039-034-MY3.
33. Yat-Yin Law, Wei-Fang Lee, Chin-Jung Hsu, Yen-You Lin, Chun-Hao Tsai, Chien-Chung Huang, Min-Huan Wu, Chih-Hsin Tang, Ju-Fang Liu (2021, Jul). miR-let-7c-5p and miR-149-5p inhibit proinflammatory cytokine production in osteoarthritis and rheumatoid arthritis synovial fibroblasts. Aging-US, 13(13):17227-17236.. (SCI, 72/194, CELL BIOLOGY; 15/54, GERIATRICS & GERONTOLOGY). MOST 108-2320-B-039-065.
34. Zhi-Hong Wen , Jhy-Shrian Huang, Yen-You Lin, Zhi-Kang Yao , Yu-Cheng Lai, Wu-Fu Chen, Hsin-Tzu Liu, Sung-Chun Lin, Yu-Chi Tsai, Tsung-Chang Tsai, Yen-Hsuan Jean (2021, Jul). Chondroprotective Effects of a Histone Deacetylase Inhibitor, Panobinostat, on Pain Behavior and Cartilage Degradation in Anterior Cruciate Ligament Transection-Induced Experimental Osteoarthritic Rats. International Journal of Molecular Sciences, 22(14):7290.. (SCI, 69/296, BIOCHEMISTRY & MOLECULAR BIOLOGY; 50/179, CHEMISTRY, MULTIDISCIPLINARY). MOST 106-2314-B-475-002. 本人為第一作者.
35. Iona J MacDonald, Chien-Chung Huang, Shan-Chi Liu, Yen-You Lin, Chih-Hsin Tang (2021, Apr). Targeting CCN Proteins in Rheumatoid Arthritis and Osteoarthritis. International Journal of Molecular Sciences, 22(9):4340.. (SCI, 69/296, BIOCHEMISTRY & MOLECULAR BIOLOGY; 50/179, CHEMISTRY, MULTIDISCIPLINARY). China Medical University Hospital: DMR-110-022.
36. Yen-You Lin, Nan-Fu Chen, San-Nan Yang, Yen-Hsuan Jean, Hsiao-Mei Kuo, Pei-Chin Chen, Chien-Wei Feng, Yu-Wei Liu, Yu-Cheng Lai, Zhi-Hong Wen (2021, Mar). Effects of Streptococcus thermophilus on anterior cruciate ligament transection-induced early osteoarthritis in rats. Experimental and Therapeutic Medicine. (SCI, 105/139; MEDICINE, RESEARCH & EXPERIMENTAL). TCI Co., Ltd: 10417. 本人為第一作者.
37. Yen-You Lin, Chih-Yuan Ko, Shan-Chi Liu, Yu-Han Wang, Chin-Jung Hsu, Chun-Hao Tsai, Tsung-Ju Wu, Chih-Hsin Tang (2021, Feb). miR-144-3p ameliorates the progression of osteoarthritis by targeting IL-1β: Potential therapeutic implication. Journal of Cellular Physiology, 2021;1–13.. (SCI, 62/194, CELL BIOLOGY; 10/81, PHYSIOLOGY). MOST 107-2320-B-039-019-MY3. 本人為第一作者.
38. Ying-Fa Chen, Po-Chang Shih, Hsiao-Mei Kuo, San-Nan Yang, Yen-You Lin, Wu-Fu Chen, Shiow-Jyu Tzou, Hsin-Tzu Liu, Nan-Fu Chen. (2020, Jun). TP3, an antimicrobial peptide, inhibits infiltration and motility of glioblastoma cells via modulating the tumor microenvironment. Cancer Medicine, 9(11):3918-3931.. (SCI, 106/245, ONCOLOGY).
39. Yen-You Lin, Yen-Hsuan Jean, Sung-Chun Lin, Chien-Wei Feng, Hsiao-Mei Kuo, Yu-Cheng Lai, Tsu-Jen Kuo, Nan-Fu Chen, Hsin-Pai Lee, Zhi-Hong Wen. (2020, Feb). Etoricoxib prevents progression of osteolysis in repeated intraarticularmonosodium urate-induced gouty arthritis in rats. Journal of Advanced Research , 24 (2020) 109–120. (SCI, 8/73, MULTIDISCIPLINARY SCIENCES). MOST 105-2314-B-475-001. 本人為第一作者.
40. Zhi‐Hong Wen Yen‐You Lin Yi‐Chen Chang Chi‐Chieh Tang Shih‐Peng Hsieh Hsin‐Pai Lee Chun‐Sung Sung Wu‐Fu Chen Chian‐Her Lee Yen‐Hsuan Jean (2019, Sep). The COX‐2 inhibitor etoricoxib reduces experimental osteoarthritis and nociception in rats: The roles of TGF‐β1 and NGF expressions in chondrocytes. European Journal of Pain, Eur J Pain. 2019 Sep 8. doi: 10.1002/ejp.1478.. (SCI, 15/34, ANESTHESIOLOGY; 103/212, CLINICAL NEUROLOGY). MOST 107-2314-B-475-001-MY3. 本人為第一作者.
41. Cheng MH; Wen, ZH; Lin YY; Chen PC; Cheng SY; Huang HL; Chong IW; Sung PJ; Tai MH; Chen NF; Kuo HM; Tsui KH. (2019, May). BA6 Induces Apoptosis via Stimulation of Reactive Oxygen Species and Inhibition of Oxidative Phosphorylation in Human Lung Cancer Cells.. Oxidative Medicine and Cellular Longevity, Oxid Med Cell Longev. 2019, 7;2019:6342104.. (SCI, 55/194, CELL BIOLOGY). MOST 106-2314-B-393-001.
42. Tseng CC, Lai YC, Kuo TJ, Su JH, Sung PJ, Feng CW, Lin YY , Chen PC, Tai MH, Cheng SY, Kuo HM, Wen ZH. (2019, Mar). Rhodoptilometrin, a Crinoid-Derived Anthraquinone, Induces Cell Regeneration by Promoting Wound Healing and Oxidative Phosphorylation in Human Gingival Fibroblast Cells.. Marine Drugs, Mar. Drugs 2019, 17(3), 138. (SCI, 10/63, CHEMISTRY, MEDICINAL; 48/279, PHARMACOLOGY & PHARMACY). MOST 106-2313-B-110-002.
43. Hung HC, Feng CW, Lin YY, Chen CH, Tsui KH4, Chen WF, Pan CY, Sheu JH, Sung CS, Wen ZH. (2018, Feb). Nucleophosmin modulates the alleviation of atopic dermatitis caused by the marine-derived compound dihydroaustrasulfone alcohol.. Experimental & Molecular Medicine, Exp Mol Med. 2018 16;50(2):e446.. (SCI, 21/296, BIOCHEMISTRY & MOLECULAR BIOLOGY; 12/139, MEDICINE, RESEARCH